The Czech Republic is easy to travel: Prague sits near the center, and Brno, Karlovy Vary and the Bohemian towns are all a few hours away by train or bus. Prague dominates in numbers, but the spa towns in the west and the Moravian cities in the east give a different and considerably quieter version of the country.
The guides here cover Prague, Brno, Karlovy Vary and the country overall. Prague's old town is at its most crowded from May to September and around Christmas; early morning is the reliable way to see the castle district and Charles Bridge with room to move. Beer culture here is regional rather than national, and the difference between towns is part of what people travel for.